Detailed Product Description:
A water-white liquid with an ethereal odor. Soluble in water and organic
solvents. Commonly used as a solvent for natural and synthetic resins
This is reagent grade material with minimum purity of 99.9%. Contains
Tetrahydrofuran (THF) is a colorless, water-miscible organic liquid with
low viscosity at standard temperature and pressure. As one of the most
polar ethers with a wide liquid range, it is a useful solvent. Its main use is
however as a precursor to polymers. THF has an odor similar to its
chemical cousin, diethyl ether, but is a much less potent anesthetic than ether.
The main application of THF is as an industrial solvent for PVC and in
varnishes. It is an aprotic solvent with a dielectric constant of 7.6. It is
a moderately polar solvent and can dissolve a wide range of nonpolar and
polar chemical compounds. THF is water-miscible, and can form solid
clathrate hydrate structures with water at low temperatures.
THF is a popular solvent in the laboratory when a higher-boiling ethereal
solvent is required and its water miscibility is not an issue. THF is a cyclic
ether, whereas diethyl ether is acyclic, so each have an oxygen atom with
two carbon substituents. Like diethyl ether, THF can be used in hydroboration
reactions to synthesize primary alcohols, and as a solvent for organometallic
compounds such as organolithium and Grignard reagents.
Although similar to ether, THF is a stronger base. Thus, while diethyl ether
remains the solvent of choice for some reactions (e.g., Grignard reactions),
THF fills that role in many others where strong coordination is desirable, and
the precise properties of ethereal solvents such as these (alone and in mixtures
and at various temperatures) allows for fine-tuning modern chemical reactions.
THF is often used in polymer science. For example, it can be used to dissolve
rubber prior to determining its molecular mass using gel permeation chromatography.
THF dissolves PVC as well and is the main ingredient in PVC adhesives. It can be
used to liquefy old PVC cement, and is often used industrially to degrease metal parts.
Extremely flammable—dangerous fire risk. Considered a relatively
nontoxic solvent, with the median lethal dose (LD50) comparable to
that of acetone. Easily penetrates skin causing rapid dehydration.
Readily dissolves latex and is typically handled with nitrile or neoprene
The greatest danger posed by THF follows from its tendency to form
highly-explosive peroxides on storage in air. To minimize this problem,
commercial samples of THF are often inhibited with BHT. THF should
not be distilled to dryness, because the explosive peroxides concentrate
in the residue.
Click here to download copy of MSDS (Material Safety Data Sheet)
Comes packed in 500ml amber glass bottle. Also available in 250ml size.